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Friday, January 28, 2022

Very important in all exam CHEMISRTRY -12

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Thursday, January 13, 2022

Class-12, Bio- notes

Notes

Chapter-10

Microbes in Human Welfare 

Introduction

Microbes (protozoa,bacteria,virus,fungi,viroids) are present every where-in soil,water,air,inside our body.
Microbes causes disease in human beings,in animals and plants but several microbes are also use-full to man in many ways.
Mostly microbes are composition (every where) and they are survive any condition like salty,very cold and high temperature.
Microbes in household products :- microbes are also   important in production of house hold. which use as daily life.
Curd:- production of curd by bacteria lactobacillus is also called LAB (lactic acid bacteria).
LAB produce lactic acid that partially digested the milk protein cogulate into curd.
Small amount of curd uses as starter (inoculum of curd add-fresh milk).
Curd is rich of vitamin-B12(Anemia).
Cheese:- It produce by a bacteria called propionibacterium Shermanii, which makes the holes in swiss cheese are ripened by the help of co2 production as a by product.
Bread:- Dough (wet flour) which is use for making bread A bacteria  saccharomyces  cerevisiae who produce CO2 in the absence of O2 that the  reseason  floar are douch.
 Dhosa,Upma,Idli:- Rice and black gram (urad) ferment for 3-9 hours with air born Lectonostoc and Steptococcus spaces of bacteri.
➤These bacteria produce CO2 during fermentation  causing puffing up of the daugh.
bacteria produce CO2 during fermentation  causing puffing up of the daugh.
Toddy:- Commonly called Tadi.
It fermented sap of palm (stem of palm).
 Microbes in Industrial production:- 
Fermented beverages,antibiotic,alcohol enzyme and  other bioactive molecule  etc produced by using microbes on industrial soil.
Fermentor:- which we grown microbes on industry in large vesscels called fermentors. 
A. Alcohal Ferm ention:- Louis pasture - Formed firmed Bear and Buttermilk with the help of yeast Saccharomyces cerevisiae (Brewer Yeast).
On those days every one unknown these things.
 
Sugar→Fermentation (yest cell)(ATP)Energy For Yest Cell→By product Ethanol (alcohal)
 
Barley(    )uses (malt)for beer.
Potato for vodka.
Apple for fenny.
Rye melt for gin.
Cereals for whisky.
Rice for sake (japanes).
Cashew for rum and fermented juice for wines and brandy.
All these beverage products are formed due to fermentation.
 
Beverage                      Type                                Alcohol %
Brandy                   Fruit                                            40-5o
Whisky                  Cereal Grains                              40-55
Rum                      Molasses/Sugarcane                  40-55
Wines                    Grapes also other fruits             10-22
Beer                       Cereals                                             4-8
Toddy                    Flower of Coconut and Palm     5-10
Arrack                   Paddy/Wheat                              50-60
 
B. Antibiotics:- G.K. world means of Anti→(Against) and Bio→(life), Antibiotics means against the disease  causing organism of life.
An antibiotic is an antimicrobial drug that is active against the bacteria.
Ex- Penicillin
       Chlormphenicol 
Term antibiotics was coined by "selman walksman 1943"
In 1928 Alexander Fleming Notice that colonies of bacteria (staphylococci) growing of a culture plate had been affected by a mould (penicillum Notatum)  
A decade earnst chain ,Howard Florey are isolated the lingredient responsibil penicillum, and show that it was highly effective against many serious bacterial pathogen. 
This led to the discovery of penicillum the first antibiotic.
This antibio highly used at world war Ⅱ.
Fleming chain and florey adwarded by noble prize in 1945 .
Ampicillin and Amoxillin which antibiotics prevent different type of pathogen are caused by microbes its called broad spectrum Antibiotics.
🟢Example of narrow spectrum antibiotics:-Its work against particular or specific pathogen. 
Ex- older pathogen (pen G).
Marcolides.
Vancomycins.

🟢Example of bactericides (KillIng bacteria):- Its working like a action means killing the bacteria 

ex- Cephalosparins (cephems)
       monobactums   and carbapenems.
🟢Example of bacteiostatics:- Its working like inhibitors Which prevents the growth of bacteria.
ex-Tetracyclines
     Sulfonamids.

Arganic acid:- Microbes are used to maked organic acid by the process of Fermented alcohol.

1. Acetic acid:- It is prepared from fermented alcohol with the help of acetic bacteria ,autobacter aceti.
 
                      Zymase                                            Zymase
C6H12O6⟶2C2H5OH+2CO2⟶C3COOH+H2O
                   Absence of O2                                          O2 Presence  
 
2.Citric acid:-It is obtained through the fermentation carried out by Aspergillus niger and muco specius an sugar syeup.
3. Lactic acid:- Lactic acid fermentation is carried out by both bacteria (streptococus lactis lactobacillus spe) and fungi  rhizopus.
 
C12H22O11+H2O⟶2C6H12O⟶4C3H4O3+4H2⟶4CH3.CHOH.COOH
 
C. Chemicals enzyme and other Bio-active Molecule:- 
Enzymes:- Industrial uses hardly 1.0 to 1.5% of the total known enzymes are used in Industrial medicines and foods,    The important ones are.
 Proteases:- They are enzyme that degrade proteins polipeptides (Along chain of proteins).
Amylase:- They degrade starch and carbohydrates.           
 

 

 

 


 

     

    
       
  

 

 

Human helth and disease